What is PZP?

The zona pellucida (ZP) is a glycoprotein membrane that surrounds all mammalian eggs. Certain proteins in the membrane serve as the sperm receptor.  The contraceptive vaccine produced by the SCC uses the ZP from the pig, thus the name porcine zona pellucida (PZP). Briefly, the PZP is produced by a complex process whereby the ZP is removed from the ovum, its glycoproteins extracted, isolated, and converted into a vaccine. The vaccine stimulates the target animal to produce antibodies, which attach to its own ZP, thus blocking fertilization and causing contraception. The PZP vaccine is usually given, initially, in a series of 2 vaccinations 2-6 weeks apart and then a booster every 8 months to a year, depending on the species. The PZP is emulsified with an adjuvant to stimulate the animal’s immune system. Please go to our Protocol page for additional information.

To have PZP shipped internationally an import permit must be obtained. The specifications of the PZP are in listed below…….